[Term]
id: PR:000045316
name: histone H4, initiator methionine removed dimethylated 1 (human)
def: "A histone H4 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-21 of the amino acid sequence represented by UniProtKB:P62805. UniProtKB:P62805, 2-103, Lys-21, MOD:00084." [PRO:DAN, PRO:JPB, PRO:JR, PMID:15200950, HIstome_var_Hs:Histone_H4]
comment: Category=organism-modification.
synonym: "hH4/InitMet-/Me2:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000158320, Lys-21, MOD:00084" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P62805, 2-103, Lys-21, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "H4:H4K20me2" BROAD [HIstome_ptm_Hs:H4K20me2]
xref: Reactome:R-HSA-5651652 "PR:000045316 located_in GO:0005654"
xref: TDR:12674
is_a: PR:P62805 ! histone H4 (human)
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens