[Term]
id: PR:000045402
name: histone H1.4, initiator methionine removed phosphorylated 8 (human)
def: "A histone H1.4 (human) that has had the initiator methionine removed and that has been phosphorylated at positions equivalent to Thr-18, Ser-27, Thr-146, Thr-154, Ser-172, and Ser-187 of the amino acid sequence represented by UniProtKB:P10412. UniProtKB:P10412, 2-219, Thr-18/Thr-146/Thr-154, MOD:00047|Ser-27/Ser-172/Ser-187, MOD:00046." [PRO:CNA, PMID:20439994, HIstome_var_Hs:Histone_H1.4]
comment: Category=organism-modification. Note: Top-down proteomics. Evidence=(ECO:0000006, based on PMID:20439994).
synonym: "hHIST1H1E/InitMet-/Phos:8" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10412, 2-219, Thr-18/Thr-146/Thr-154, MOD:00047|Ser-27/Ser-172/Ser-187, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "6p-H1.4" BROAD [PMID:20439994]
synonym: "H1.4:H1S171ph" BROAD [HIstome_ptm_Hs:H1S171ph]
synonym: "H1.4:H1S186ph" BROAD [HIstome_ptm_Hs:H1S186ph]
is_a: PR:P10412 ! histone H1.4 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens