[Term]
id: PR:000045488
name: interferon regulatory factor 3 phosphorylated 1 (human)
def: "An interferon regulatory factor 3 (human) that has been phosphorylated on residues at positions equivalent to Ser-396, Ser-398, Ser-402, Thr-404, and Ser-405 of the amino acid sequence represented by UniProtKB:Q14653-1. Example: UniProtKB:Q14653-1, Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, PRO:DAN, Reactome:R-HSA-166258, Reactome:R-HSA-177654]
comment: Category=organism-modification. Note: Ser-386 is within the 2S site while Ser-396, Ser-498, Ser-402, Thr-404, and Ser-405 are within the 5ST site.
synonym: "hIRF3/Phos:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q14653, Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "p-4S,T404-IRF3 (human)" RELATED []
synonym: "UniProtKB:Q14653-1, Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:Q14653-2, Ser-259/Ser-271/Ser-275/Ser-278, MOD:00046|Thr-277, MOD:00047" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:Q14653-3, Ser-113/Ser-125/Ser-129/Ser-132, MOD:00046|Thr-131, MOD:00047" NARROW PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-166258 "PR:000045488 located_in GO:0005829"
xref: Reactome:R-HSA-177654 "PR:000045488 located_in GO:0005654"
is_a: PR:Q14653 ! interferon regulatory factor 3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens