[Term]
id: PR:000045691
name: sphingomyelin phosphodiesterase phosphorylated 1 (human)
def: "A sphingomyelin phosphodiesterase (human) that has been phosphorylated on the residue at the position equivalent to Ser-510 of the amino acid sequence represented by UniProtKB:P17405-1. Example: UniProtKB:P17405-1, Ser-510, MOD:00046." [PRO:DAN, PMID:17303575, iPTMnet:P17405]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:17303575). Note: The modified site indicated here (Ser-510) is referred to as Ser-508 in the literature, likely based on a two-residue-shorter isoform (UniProtKB:E9LUE6). [PRO:DAN, PMID:17303575]
synonym: "hSMPD1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P17405, Ser-510, MOD:00046" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P17405-1, Ser-510, MOD:00046" NARROW PRO-proteoform-std [PRO:DAN]
is_a: PR:P17405 ! sphingomyelin phosphodiesterase (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens