[Term]
id: PR:000046371
name: serine/threonine-protein kinase A-Raf phosphorylated 1 (human)
def: "A serine/threonine-protein kinase A-Raf (human) that has been post-translationally modified to include phosphoserine at positions 214 and 582 of the amino acid sequence represented by UniProtKB:P10398. UniProtKB:P10398, Ser-214/Ser-582, MOD:00046." [PRO:DAN, Reactome:R-HSA-5672639]
comment: Category=organism-modification. Note: The modified site indicated here (Ser-582) is referred to as Ser-576 in some manuscripts. [PRO:DAN, PMID:21779496]
synonym: "hARAF/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10398, Ser-214/Ser-582, MOD:00046" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-5672639 "PR:000046371 located_in GO:0005829"
is_a: PR:P10398 ! serine/threonine-protein kinase A-Raf (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens