[Term]
id: PR:000046454
name: beta-secretase 1, signal peptide removed acetylated 1 (human)
def: "A beta-secretase 1 (human) that has had the signal peptide removed and has been post-translationally modified to include N6-acetyllysine at positions 126, 275, 279, 285, 299, 300 and 307 of the amino acid sequence represented by UniProtKB:P56817. UniProtKB:P56817, 22-501, Lys-126/Lys-275/Lys-279/Lys-285/Lys-299/Lys-300/Lys-307, MOD:00064." [PRO:DNx, Reactome:R-HSA-5693006, Reactome:R-HSA-5693095]
comment: Category=organism-modification.
synonym: "hBACE1/SigPep-/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P56817, 22-501, Lys-126/Lys-275/Lys-279/Lys-285/Lys-299/Lys-300/Lys-307, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5693006 "PR:000046454 located_in GO:0005788"
xref: Reactome:R-HSA-5693095 "PR:000046454 located_in GO:0070931"
is_a: PR:P56817 ! beta-secretase 1 (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens