[Term]
id: PR:000047138
name: lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial, transit peptide removed lipoylated 1 (human)
def: "A lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (human) that has had the transit peptide removed and has been post-translationally modified to include lipoylated lysine at position 105 of the amino acid sequence represented by UniProtKB:P11182. UniProtKB:P11182, 62-482, Lys-105, MOD:00127." [PRO:DAN, Reactome:R-HSA-70017]
comment: Category=organism-modification. Note: The modified site indicated here (Lys-105) is referred to as Lys-44 in some manuscripts. [PRO:DAN, PMID:11839747]
synonym: "hDBT/TransPep-/Lipo:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000020489, Lys-105, MOD:00127" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:P11182, 62-482, Lys-105, MOD:00127" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-70017 "PR:000047138 located_in GO:0005759"
is_a: PR:P11182 ! lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (human)
relationship: has_part MOD:00127 ! N6-lipoyl-L-lysine
relationship: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens