[Term]
id: PR:000047466
name: tyrosine-protein kinase Fyn, initiator methionine removed phosphorylated 2 (human)
def: "A tyrosine-protein kinase Fyn (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at position 21, and phosphotyrosine at position 420 of the amino acid sequence represented by UniProtKB:P06241. UniProtKB:P06241, 2-537, Ser-21, MOD:00046|Tyr-420, MOD:00048." [PRO:DNx, Reactome:R-HSA-5218745]
comment: Category=organism-modification.
synonym: "hFYN/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000088099, Ser-21, MOD:00046|Tyr-420, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P06241, 2-537, Ser-21, MOD:00046|Tyr-420, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5218745 "PR:000047466 located_in GO:0005829"
is_a: PR:P06241 ! tyrosine-protein kinase Fyn (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens