[Term]
id: PR:000048314
name: mitogen-activated protein kinase 1, initiator methionine removed phosphorylated 1 (human)
def: "A mitogen-activated protein kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 185, and phosphotyrosine at position 187 of the amino acid sequence represented by UniProtKB:P28482. UniProtKB:P28482, 2-360, Thr-185, MOD:00047|Tyr-187, MOD:00048." [PRO:DNx, Reactome:R-HSA-109853, Reactome:R-HSA-112354]
comment: Category=organism-modification.
synonym: "hMAPK1/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000186247, Thr-185, MOD:00047|Tyr-187, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P28482, 2-360, Thr-185, MOD:00047|Tyr-187, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-109853 "PR:000048314 located_in GO:0005829"
xref: Reactome:R-HSA-112354 "PR:000048314 located_in GO:0005654"
is_a: PR:P28482 ! mitogen-activated protein kinase 1 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens