[Term]
id: PR:000048327
name: mitogen-activated protein kinase 7, initiator methionine removed phosphorylated 2 (human)
def: "A mitogen-activated protein kinase 7 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 219, and phosphotyrosine at position 221 of the amino acid sequence represented by UniProtKB:Q13164. UniProtKB:Q13164, 2-816, Thr-219, MOD:00047|Tyr-221, MOD:00048." [PRO:DAN, PMID:12628002, Reactome:R-HSA-198721, Reactome:R-HSA-198738]
comment: Category=organism-modification. Note: The modified site indicated here (Thr-219/Tyr-221) is referred to as Thr-218/Tyr-220 in the literature using the rat sequence. [PRO:DAN, PMID:11544482]
synonym: "hMAPK7/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000186260, Thr-219, MOD:00047|Tyr-221, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:Q13164, 2-816, Thr-219, MOD:00047|Tyr-221, MOD:00048" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-198721 "PR:000048327 located_in GO:0005829"
xref: Reactome:R-HSA-198738 "PR:000048327 located_in GO:0005654"
is_a: PR:Q13164 ! mitogen-activated protein kinase 7 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens