[Term]
id: PR:000048358
name: E3 ubiquitin-protein ligase Mdm2 phosphorylated 3 (human)
def: "An E3 ubiquitin-protein ligase Mdm2 (human) that has been post-translationally modified to include phosphoserine at positions 166 and 188, and phosphothreonine at position 218 of the amino acid sequence represented by UniProtKB:Q00987. UniProtKB:Q00987, Ser-166/Ser-188, MOD:00046|Thr-218, MOD:00047." [PRO:DNx, Reactome:R-HSA-6792862]
comment: Category=organism-modification.
synonym: "hMDM2/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q00987, Ser-166/Ser-188, MOD:00046|Thr-218, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6792862 "PR:000048358 located_in GO:0005654"
is_a: PR:Q00987 ! E3 ubiquitin-protein ligase Mdm2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens