[Term]
id: PR:000048644
name: high affinity nerve growth factor receptor, signal peptide removed phosphorylated 1 (human)
def: "A high affinity nerve growth factor receptor (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 496, 676, 680, 681 and 791 of the amino acid sequence represented by UniProtKB:P04629. UniProtKB:P04629, 33-796, Tyr-496/Tyr-676/Tyr-680/Tyr-681/Tyr-791, MOD:00048." [PRO:DAN, Reactome:R-HSA-3008810, Reactome:R-HSA-3009413]
comment: Category=organism-modification. Note: The modified site indicated here (Tyr-496/Tyr-676/Tyr-680/Tyr-681/Tyr-791) are referred to as Tyr-490/Tyr-670/Tyr-674/Tyr-675/Tyr-785 in the literature using the rat sequence. [PRO:DAN, PMID:9099755]
synonym: "hNTRK1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000016724, Tyr-496/Tyr-676/Tyr-680/Tyr-681/Tyr-791, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P04629, 33-796, Tyr-496/Tyr-676/Tyr-680/Tyr-681/Tyr-791, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3008810 "PR:000048644 located_in GO:0000139"
xref: Reactome:R-HSA-3009413 "PR:000048644 located_in GO:0005886"
is_a: PR:P04629 ! high affinity nerve growth factor receptor (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens