[Term]
id: PR:000048646
name: BDNF/NT-3 growth factors receptor, signal peptide removed phosphorylated 1 (human)
def: "A BDNF/NT-3 growth factors receptor (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 516, 702, 706, 706 and 817 of the amino acid sequence represented by UniProtKB:Q16620. UniProtKB:Q16620, 32-822, Tyr-516/Tyr-702/Tyr-706/Tyr-707/Tyr-817, MOD:00048." [PRO:DAN, Reactome:R-HSA-3008809]
comment: Category=organism-modification. Note: The modified sites indicated here (Tyr-516/Tyr-701/Tyr-705/Tyr-706/Tyr-817) are referred to as Tyr-490/Tyr-670/Tyr-674/Tyr-675/Tyr-785 in the literature using the rat sequence. [PRO:DAN, PMID:8106527]
synonym: "hNTRK2/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000016727, Tyr-516/Tyr-702/Tyr-706/Tyr-707/Tyr-817, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q16620, 32-822, Tyr-516/Tyr-702/Tyr-706/Tyr-707/Tyr-817, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3008809 "PR:000048646 located_in GO:0000139"
xref: Reactome:R-HSA-9026475 "PR:000048646 located_in GO:0005886"
is_a: PR:Q16620 ! BDNF/NT-3 growth factors receptor (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens