[Term]
id: PR:000048912
name: protein kinase C alpha type, initiator methionine removed phosphorylated 2 (human)
def: "A protein kinase C alpha type (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at positions 497 and 638, and phosphoserine at position 657 of the amino acid sequence represented by UniProtKB:P17252. UniProtKB:P17252, 2-672, Thr-497/Thr-638, MOD:00047|Ser-657, MOD:00046." [PRO:DNx, Reactome:R-HSA-4332337, Reactome:R-HSA-4332340, Reactome:R-HSA-5223292]
comment: Category=organism-modification.
synonym: "hPRKCA/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000055679, Thr-497/Thr-638, MOD:00047|Ser-657, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P17252, 2-672, Thr-497/Thr-638, MOD:00047|Ser-657, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4332337 "PR:000048912 located_in GO:0005829"
xref: Reactome:R-HSA-4332340 "PR:000048912 located_in GO:0005886"
xref: Reactome:R-HSA-5223292 "PR:000048912 located_in GO:0005654"
is_a: PR:P17252 ! protein kinase C alpha type (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens