[Term]
id: PR:000048998
name: RAF proto-oncogene serine/threonine-protein kinase phosphorylated 4 (human)
def: "A RAF proto-oncogene serine/threonine-protein kinase (human) that has been post-translationally modified to include phosphoserine at positions 29, 43, 259, 296, 301, 338, 494, 621 and 642, phosphotyrosine at position 341, and phosphothreonine at position 491 of the amino acid sequence represented by UniProtKB:P04049. UniProtKB:P04049, Ser-29/Ser-43/Ser-259/Ser-296/Ser-301/Ser-338/Ser-494/Ser-621/Ser-642, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-5675193]
comment: Category=organism-modification.
synonym: "hRAF1/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P04049, Ser-29/Ser-43/Ser-259/Ser-296/Ser-301/Ser-338/Ser-494/Ser-621/Ser-642, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5675193 "PR:000048998 located_in GO:0005886"
is_a: PR:P04049 ! RAF proto-oncogene serine/threonine-protein kinase (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens