[Term]
id: PR:000049001
name: RAF proto-oncogene serine/threonine-protein kinase phosphorylated 7 (human)
def: "A RAF proto-oncogene serine/threonine-protein kinase (human) that has been post-translationally modified to include phosphoserine at positions 338, 494 and 621, phosphotyrosine at position 341, and phosphothreonine at position 491 of the amino acid sequence represented by UniProtKB:P04049. UniProtKB:P04049, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-5672664, Reactome:R-HSA-5672665]
comment: Category=organism-modification.
synonym: "hRAF1/Phos:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P04049, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5672664 "PR:000049001 located_in GO:0005829"
xref: Reactome:R-HSA-5672665 "PR:000049001 located_in GO:0005886"
is_a: PR:P04049 ! RAF proto-oncogene serine/threonine-protein kinase (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens