[Term]
id: PR:000049042
name: proto-oncogene tyrosine-protein kinase receptor Ret, signal peptide removed phosphorylated 2 (human)
def: "A proto-oncogene tyrosine-protein kinase receptor Ret (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 905, 981, 1015, 1062 and 1096 of the amino acid sequence represented by UniProtKB:P07949. UniProtKB:P07949, 29-1114, Tyr-905/Tyr-981/Tyr-1015/Tyr-1062/Tyr-1096, MOD:00048." [PRO:DNx, Reactome:R-HSA-8854162]
comment: Category=organism-modification.
synonym: "hRET/SigPep-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000024450, Tyr-905/Tyr-981/Tyr-1015/Tyr-1062/Tyr-1096, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P07949, 29-1114, Tyr-905/Tyr-981/Tyr-1015/Tyr-1062/Tyr-1096, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8854162 "PR:000049042 located_in GO:0005886"
is_a: PR:P07949 ! proto-oncogene tyrosine-protein kinase receptor Ret (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens