[Term]
id: PR:000049135
name: ribosomal protein S6 kinase beta-1 phosphorylated 2 (human)
def: "A ribosomal protein S6 kinase beta-1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-394, and phosphothreonine at position 412 of the amino acid sequence represented by UniProtKB:P23443. UniProtKB:P23443, Ser-394, MOD:00046|Thr-412, MOD:00047." [PRO:DAN, Reactome:R-HSA-165714]
comment: Category=organism-modification. Note: Numbering in some publications reflect that of isoform known at the time, which is now the shorter isoform (-2; with modifications at Ser-371 and Thr-394).
synonym: "hRPS6KB1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P23443, Ser-394, MOD:00046|Thr-412, MOD:00047" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P23443-1, Ser-394, MOD:00046|Thr-412, MOD:00047" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P23443-2, Ser-371, MOD:00046|Thr-389, MOD:00047" NARROW PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-165714 "PR:000049135 located_in GO:0005829"
is_a: PR:P23443 ! ribosomal protein S6 kinase beta-1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens