[Term]
id: PR:000049236
name: serine hydroxymethyltransferase, cytosolic, initiator methionine removed pyridoxal phosphate lysine 1 (human)
def: "A serine hydroxymethyltransferase, cytosolic (human) that has had the initiator methionine removed and has been post-translationally modified to include pyridoxal phosphate lysine at position 257 of the amino acid sequence represented by UniProtKB:P34896. UniProtKB:P34896, 2-483, Lys-257, MOD:00128." [PRO:DNx, Reactome:R-HSA-71242]
comment: Category=organism-modification.
synonym: "hSHMT1/InitMet-/Pyrdox:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000113504, Lys-257, MOD:00128" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P34896, 2-483, Lys-257, MOD:00128" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-71242 "PR:000049236 located_in GO:0005829"
is_a: PR:P34896 ! serine hydroxymethyltransferase, cytosolic (human)
relationship: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens