[Term]
id: PR:000049283
name: mothers against decapentaplegic homolog 2, initiator methionine removed phosphorylated 5 (human)
def: "A mothers against decapentaplegic homolog 2 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 220, and phosphoserine at positions 465 and 467 of the amino acid sequence represented by UniProtKB:Q15796. UniProtKB:Q15796, 2-467, Thr-220, MOD:00047|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3009189]
comment: Category=organism-modification.
synonym: "hSMAD2/InitMet-/Phos:5" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000090852, Thr-220, MOD:00047|Ser-465/Ser-467, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q15796, 2-467, Thr-220, MOD:00047|Ser-465/Ser-467, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3009189 "PR:000049283 located_in GO:0005654"
is_a: PR:Q15796 ! mothers against decapentaplegic homolog 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens