[Term]
id: PR:000049298
name: protein smoothened, signal peptide removed phosphorylated 1 (human)
def: "A protein smoothened (human) that has had the signal peptide removed and has been post-translationally modified to include phosphoserine at positions 588, 590 and 595, and phosphothreonine at position 593 of the amino acid sequence represented by UniProtKB:Q99835. UniProtKB:Q99835, 28-787, Ser-588/Ser-590/Ser-595, MOD:00046|Thr-593, MOD:00047." [PRO:DNx, Reactome:R-HSA-5632525]
comment: Category=organism-modification.
synonym: "hSMO/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000013015, Ser-588/Ser-590/Ser-595, MOD:00046|Thr-593, MOD:00047" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q99835, 28-787, Ser-588/Ser-590/Ser-595, MOD:00046|Thr-593, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5632525 "PR:000049298 located_in GO:0060170"
is_a: PR:Q99835 ! protein smoothened (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens