[Term]
id: PR:000049451
name: Rho guanine nucleotide exchange factor TIAM1, initiator methionine removed phosphorylated 1 (human)
def: "A Rho guanine nucleotide exchange factor TIAM1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at position 829 of the amino acid sequence represented by UniProtKB:Q13009. UniProtKB:Q13009, 2-1591, Tyr-829, MOD:00048." [PRO:DNx, Reactome:R-HSA-3928461]
comment: Category=organism-modification.
synonym: "hTIAM1/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000080976, Tyr-829, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q13009, 2-1591, Tyr-829, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3928461 "PR:000049451 located_in GO:0005829"
is_a: PR:Q13009 ! Rho guanine nucleotide exchange factor TIAM1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens