[Term]
id: PR:000049855
name: protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human)
def: "A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500 of the activation loop, and phosphothreonine at position 641 and phosphoserine at position 660 of the Pkinase_C domain (Pfam:PF00433). UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046." [PRO:KER, PMID:8749392]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:8749392). Kinase=("PRKCB"; PR:P05771; Thr-641/Ser-660).
synonym: "hPRKCB/iso:Beta-II/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P05771-2 ! protein kinase C beta type isoform Beta-II (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: lacks_part PR:000021937 ! initiator methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens