[Term]
id: PR:000049957
name: high affinity nerve growth factor receptor isoform TrkA-I mature form N-glycosylated and phosphorylated 1 (human)
def: "A high affinity nerve growth factor receptor isoform TrkA-I (human) that has had the signal peptide removed, is N-glycosylated and has been post-translationally modified to include phosphotyrosine at position 490. UniProtKB:P04629-2, 33-790, Tyr-490, MOD:00048|MOD:00160." [PRO:LN, PMID:27655914]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:27655914). Kinase=("NTRK1"; PR:P04629; Tyr-490).
synonym: "hNTRK1/iso:TrkA-I/mature/NGlycoPhos:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P04629-2, 33-790, Tyr-490, MOD:00048|MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "140-KDa TrkA Tyr(P)-490" RELATED [PMID:27655914]
is_a: PR:P04629-2 ! high affinity nerve growth factor receptor isoform TrkA-I (human)
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens