[Term]
id: PR:000050270
name: host translation inhibitor nsp1 (SARS-CoV-2)
def: "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the N-terminal portion produced by the enzymatic action of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 180-181." [PRO:DAN, GenPept:YP_009725297, UniProtKB:P0DTC1, UniProtKB:P0DTD1]
comment: Category=organism-modification. Note: 180 aa protein. Proteinase inferred from PMID:15564471.
synonym: "rep/Clv:nsp1 (SARS2)" EXACT PRO-short-label [PRO:DAN]
synonym: "leader protein (SARS-CoV-2)" EXACT [UniProtKB:P0DTC1, UniProtKB:P0DTD1]
synonym: "non-structural protein 1 (SARS-CoV-2)" EXACT [UniProtKB:P0DTC1, UniProtKB:P0DTD1]
synonym: "nsp1 (SARS-CoV-2)" EXACT [UniProtKB:P0DTC1, UniProtKB:P0DTD1]
synonym: "PRO_0000449619" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "PRO_0000449635" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:P0DTC1, 1-180" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P0DTD1, 1-180" EXACT PRO-proteoform-std [PRO:DAN]
xref: GenPept:YP_009725297
xref: GenPept:YP_009742608
is_a: PR:000050281 ! rep gene proteolytic cleavage product (SARS-CoV-2)
relationship: only_in_taxon NCBITaxon:2697049 ! Severe acute respiratory syndrome coronavirus 2