[Term]
id: PR:000050273
name: non-structural protein 4 (SARS-CoV-2)
def: "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the combined actions of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 2763-2764, and 3CL-PRO (nsp5) when it cleaves the precursor between residues 3263-3264." [PRO:DAN, GenPept:YP_009725300, UniProtKB:P0DTC1, UniProtKB:P0DTD1]
comment: Category=organism-modification. Note: 500 aa protein.
synonym: "rep/Clv:nsp4 (SARS2)" EXACT PRO-short-label [PRO:DAN]
synonym: "nsp4 (SARS-CoV-2)" EXACT [UniProtKB:P0DTC1, UniProtKB:P0DTD1]
synonym: "PRO_0000449622" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "PRO_0000449638" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:P0DTC1, 2764-3263" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P0DTD1, 2764-3263" EXACT PRO-proteoform-std [PRO:DAN]
xref: GenPept:YP_009725300
xref: GenPept:YP_009742611
is_a: PR:000050281 ! rep gene proteolytic cleavage product (SARS-CoV-2)
relationship: only_in_taxon NCBITaxon:2697049 ! Severe acute respiratory syndrome coronavirus 2