[Term]
id: PR:000050274
name: 3C-like proteinase nsp5 (SARS-CoV-2)
def: "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the autocatalytic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 3263-3264 and 3569-3570." [PRO:DAN, GenPept:YP_009725301, UniProtKB:P0DTC1, UniProtKB:P0DTD1]
comment: Category=organism-modification. Note: 306 aa protein.
synonym: "rep/Clv:nsp5 (SARS2)" EXACT PRO-short-label [PRO:DAN]
synonym: "3CL-PRO (SARS-CoV-2)" EXACT [UniProtKB:P0DTC1, UniProtKB:P0DTD1]
synonym: "3CLp (SARS-CoV-2)" EXACT [UniProtKB:P0DTC1, UniProtKB:P0DTD1]
synonym: "3CLpro (SARS-CoV-2)" EXACT [PRO:DAN, PMID:15564471]
synonym: "nsp5 (SARS-CoV-2)" EXACT [UniProtKB:P0DTC1, UniProtKB:P0DTD1]
synonym: "picornavirus 3C-like protease (SARS-CoV-2)" EXACT [PRO:DAN, PMID:15564471]
synonym: "PRO_0000449623" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "PRO_0000449639" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:P0DTC1, 3264-3569" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P0DTD1, 3264-3569" EXACT PRO-proteoform-std [PRO:DAN]
xref: GenPept:YP_009725301
xref: GenPept:YP_009742612
is_a: PR:000050281 ! rep gene proteolytic cleavage product (SARS-CoV-2)
relationship: only_in_taxon NCBITaxon:2697049 ! Severe acute respiratory syndrome coronavirus 2