[Term]
id: PR:000050305
name: IgG1 immunoglobulin complex (human)
def: "An IgG immunoglobulin complex in human that is composed of two identical immunoglobulin heavy chains of an IgG1 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds. An IgG1 immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [PRO:ADD, PMID:25368619, GOC:add]
comment: Category=organism-complex. Requested by=HIPC. Requested by=CL. Note: An IgG1 immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
synonym: "hIgG1" EXACT PRO-short-label [PRO:ADD, GOC:add]
synonym: "IgG1 (human)" EXACT [PRO:ADD, GOC:add]
synonym: "IgG (human)" BROAD [PRO:ADD, GOC:add]
synonym: "IgG1 antibody (human)" NARROW [PRO:ADD, GOC:add]
is_a: GO:0071735 ! IgG immunoglobulin complex
relationship: has_component PR:000050291 {cardinality="2"} ! IgG1 heavy chain protein (human)
relationship: has_component PR:000050183 {cardinality="2"} ! immunoglobulin light chain protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens