[Term]
id: PR:000050307
name: IgG3 immunoglobulin complex (human)
def: "An IgG immunoglobulin complex in human that is composed of two identical immunoglobulin heavy chains of an IgG3 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds. An IgG3 immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [PRO:ADD, PMID:25368619, GOC:add]
comment: Category=organism-complex. Requested by=HIPC. Requested by=CL. Note: An IgG3 immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
synonym: "hIgG3" EXACT PRO-short-label [PRO:ADD, GOC:add]
synonym: "IgG3 (human)" EXACT [PRO:ADD, GOC:add]
synonym: "IgG (human)" BROAD [PRO:ADD, GOC:add]
synonym: "IgG3 antibody (human)" NARROW [PRO:ADD, GOC:add]
is_a: GO:0071735 ! IgG immunoglobulin complex
relationship: has_component PR:000050293 {cardinality="2"} ! IgG3 heavy chain protein (human)
relationship: has_component PR:000050183 {cardinality="2"} ! immunoglobulin light chain protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens