[Term]
id: PR:000050315
name: IgG3 B cell receptor complex (human)
def: "An IgG3 immunoglobulin complex (human) that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the membrane-bound isoform of the IgG3 isotype, two identical immunoglobulin light chains (kappa or lambda), and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [PRO:ADD, PMID:17496345, GOC:add, ISBN:0781765196]
comment: Category=organism-complex. Requested by=HIPC. Requested by=CL.
synonym: "hIgG3/B-cell-receptor" EXACT PRO-short-label [PRO:ADD, GOC:add]
synonym: "membrane-bound IgG3 (human)" EXACT [PRO:ADD, GOC:add]
synonym: "surface IgG3 (human)" EXACT [PRO:ADD, GOC:add]
synonym: "membrane-bound IgG (human)" BROAD [PRO:ADD, GOC:add]
synonym: "surface IgG (human)" BROAD [PRO:ADD, GOC:add]
is_a: PR:000050307 ! IgG3 immunoglobulin complex (human)
relationship: has_component PR:000050303 {cardinality="2"} ! IgG3 heavy chain protein, membrane-bound isoform (human)
relationship: has_component PR:000050183 {cardinality="2"} ! immunoglobulin light chain protein (human)
relationship: has_component PR:P11912 {cardinality="1"} ! B-cell antigen receptor complex-associated protein alpha chain (human)
relationship: has_component PR:P40259 {cardinality="1"} ! B-cell antigen receptor complex-associated protein beta chain (human)
relationship: part_of CL:0000236 ! B cell
relationship: part_of GO:0005886 ! plasma membrane
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens