[Term]
id: PR:000060212
name: histone H2AX acetylated, dimethylated, and monomethylated 1 (Dictyostelium discoideum)
def: "A histone H2AX (Dictyostelium discoideum) that has been dimethylated at the positions equivalent to Ser-9 and Lys-10, monomethylated at the position equivalent to Lys-18, and acetylated at the position equivalent to Lys-19 of the amino acid sequence represented by UniProtKB:Q54WG6. Note that the indicated residues are called Ser-8, Lys-9, Lys-17, and Lys-18, respectively, in the literature, based on sequence numbering that accounts for a removed initiator methionine. UniProtKB:Q54WG6, Ser-9, MOD:01783|Lys-10, MOD:00084|Lys-18, MOD:00085|Lys-19, MOD:00064." [PRO:DAN, dictyBase:PF, PMID:33947439]
comment: Category=organism-modification. Requested by=dictyBase. Note: In vivo. Contains H2AXS8me2, H2AXK9me2, H2AXK17me1, and H2AXK18ac.
synonym: "Dicty-H2AX/AcMe1Me2:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q54WG6, Ser-9, MOD:01783|Lys-10, MOD:00084|Lys-18, MOD:00085|Lys-19, MOD:00064" EXACT PRO-proteoform-std [PRO:DAN]
is_a: PR:Q54WG6 ! histone H2AX (Dictyostelium discoideum)
relationship: has_part MOD:01783 ! N,N-dimethyl-L-serine
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: has_part MOD:00085 ! N6-methyl-L-lysine
relationship: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum