[Term]
id: PR:000060376
name: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, initiator methionine removed phosphorylated 1 (human)
def: "A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Tyr-336 of the amino acid sequence represented by UniProtKB:P60484-1. Example: UniProtKB:P60484-1, 2-403, Tyr-336, MOD:00048." [PRO:DNx, Reactome:R-HSA-8847980]
comment: Category=organism-modification.
synonym: "hPTEN/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-Y336-PTEN" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-8847980]
synonym: "UniProtKB:P60484, 2-403, Tyr-336, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P60484-1, 2-403, Tyr-336, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8847980 "PR:000060376 located_in GO:0005829"
is_a: PR:P60484 ! phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens