[Term]
id: PR:000060624
name: fibroblast growth factor receptor 3 sequence variant Y373C, signal peptide removed phosphorylated 1 (human)
def: "A fibroblast growth factor receptor 3 (human) that has a Cys residue at the position equivalent to Tyr-373 of the amino acid sequence represented by UniProtKB:P22607-1, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Tyr-577, Tyr-647, Tyr-648, Tyr-724, Tyr-760, and Tyr-770. Example: UniProtKB:P22607-1, 23-806, Tyr-373, CHEBI:29950|Tyr-577/Tyr-647/Tyr-648/Tyr-724/Tyr-760/Tyr-770, MOD:00048." [PRO:DNx, Reactome:R-HSA-2011889]
comment: Category=organism-modification.
synonym: "hFGFR3/var:Y373C/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-6Y-FGFR3 Y373C" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-2011889]
synonym: "UniProtKB:P22607, 23-806, Tyr-373, CHEBI:29950|Tyr-577/Tyr-647/Tyr-648/Tyr-724/Tyr-760/Tyr-770, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P22607-1, 23-806, Tyr-373, CHEBI:29950|Tyr-577/Tyr-647/Tyr-648/Tyr-724/Tyr-760/Tyr-770, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2011889 "PR:000060624 located_in GO:0005886"
is_a: PR:P22607 ! fibroblast growth factor receptor 3 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens