[Term]
id: PR:000060737
name: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN sequence variant R189*, initiator methionine removed form (human)
def: "A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (human) that has has been truncated after the position equivalent to Tyr-188 of the amino acid sequence represented by UniProtKB:P60484-1 and that has had the initiator methionine removed. Example: UniProtKB:P60484-1, 2-188." [PRO:DNx, Reactome:R-HSA-9659354]
comment: Category=organism-modification.
synonym: "hPTEN/var:R189*/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PTEN R189*" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9659354]
synonym: "UniProtKB:P60484, 2-188" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P60484-1, 2-188" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9659354 "PR:000060737 located_in GO:0005829"
is_a: PR:P60484 ! phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens