[Term]
id: PR:000060774
name: fibroblast growth factor receptor 4 sequence variant V550L, signal peptide removed phosphorylated 1 (human)
def: "A fibroblast growth factor receptor 4 (human) that has a Leu residue at the position equivalent to Val-550 of the amino acid sequence represented by UniProtKB:P22455-1, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Tyr-642, Tyr-643, Tyr-719, Tyr-754, and Tyr-764. Example: UniProtKB:P22455-1, 22-802, Val-550, CHEBI:30006|Tyr-642/Tyr-643/Tyr-719/Tyr-754/Tyr-764, MOD:00048." [PRO:DNx, Reactome:R-HSA-2038935]
comment: Category=organism-modification.
synonym: "hFGFR4/var:V550L/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-5Y-FGFR4 V550L" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-2038935]
synonym: "UniProtKB:P22455, 22-802, Val-550, CHEBI:30006|Tyr-642/Tyr-643/Tyr-719/Tyr-754/Tyr-764, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P22455-1, 22-802, Val-550, CHEBI:30006|Tyr-642/Tyr-643/Tyr-719/Tyr-754/Tyr-764, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2038935 "PR:000060774 located_in GO:0005886"
is_a: PR:P22455 ! fibroblast growth factor receptor 4 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens