[Term]
id: PR:000060811
name: ALK tyrosine kinase receptor sequence variant M1166T, signal peptide removed phosphorylated 1 (human)
def: "An ALK tyrosine kinase receptor (human) that has a Thr residue at the position equivalent to Met-1166 of the amino acid sequence represented by UniProtKB:Q9UM73, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Tyr-1096, Tyr-1278, Tyr-1282, Tyr-1283, Val-1358, Tyr-1507, and Tyr-1604. UniProtKB:Q9UM73, 19-1620, Tyr-1096/Tyr-1278/Tyr-1282/Tyr-1283/Val-1358/Tyr-1507/Tyr-1604, MOD:00048|Met-1166, CHEBI:30013." [PRO:DNx, Reactome:R-HSA-9700486]
comment: Category=organism-modification.
synonym: "hALK/var:M1166T/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-7Y ALK M1166T" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9700486]
synonym: "UniProtKB:Q9UM73, 19-1620, Tyr-1096/Tyr-1278/Tyr-1282/Tyr-1283/Val-1358/Tyr-1507/Tyr-1604, MOD:00048|Met-1166, CHEBI:30013" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9700486 "PR:000060811 located_in GO:0005886"
is_a: PR:Q9UM73 ! ALK tyrosine kinase receptor (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens