[Term]
id: PR:000060890
name: TGF-beta receptor type-1 sequence variant R414*, signal peptide removed phosphorylated 1 (human)
def: "A TGF-beta receptor type-1 (human) that has has been truncated after the position equivalent to Arg-413 of the amino acid sequence represented by UniProtKB:P36897-1, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-165, Thr-185, Thr-186, Ser-187, Ser-189, and Ser-191. Example: UniProtKB:P36897-1, 34-413, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047." [PRO:DNx, Reactome:R-HSA-3656508]
comment: Category=organism-modification.
synonym: "hTGFBR1/var:R414*/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-4S,T185,T186-TGFBR1 R414*" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-3656508]
synonym: "UniProtKB:P36897, 34-413, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P36897-1, 34-413, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3656508 "PR:000060890 located_in GO:0005886"
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens