[Term]
id: PR:000061076
name: receptor tyrosine-protein kinase erbB-2 sequence variant L755M, signal peptide removed form (human)
def: "A receptor tyrosine-protein kinase erbB-2 (human) that has a Met residue at the position equivalent to Leu-755 of the amino acid sequence represented by UniProtKB:P04626-1 and that has had the signal peptide removed. Example: UniProtKB:P04626-1, 23-1255, Leu-755, CHEBI:16044." [PRO:DNx, Reactome:R-HSA-9646517]
comment: Category=organism-modification.
synonym: "hERBB2/var:L755M/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "ERBB2 L755M" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9646517]
synonym: "UniProtKB:P04626, 23-1255, Leu-755, CHEBI:16044" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P04626-1, 23-1255, Leu-755, CHEBI:16044" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9646517 "PR:000061076 located_in GO:0005886"
is_a: PR:P04626 ! receptor tyrosine-protein kinase erbB-2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens