[Term]
id: PR:000061082
name: fibroblast growth factor receptor 2 isoform 1 sequence variant W290G, signal peptide removed phosphorylated 1 (human)
def: "A fibroblast growth factor receptor 2 isoform 1 (human) that has a Gly residue at the position equivalent to Trp-290 of the amino acid sequence represented by UniProtKB:P21802-1, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Tyr-466, Tyr-586, Tyr-588, Tyr-656, Tyr-657, Tyr-733, Tyr-769, and Tyr-779. UniProtKB:P21802-1, 22-821, Trp-290, CHEBI:29947|Tyr-466/Tyr-586/Tyr-588/Tyr-656/Tyr-657/Tyr-733/Tyr-769/Tyr-779, MOD:00048." [PRO:DNx, Reactome:R-HSA-2029862]
comment: Category=organism-modification.
synonym: "hFGFR2/iso:1/var:W290G/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-8Y-FGFR2c W290G" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-2029862]
synonym: "UniProtKB:P21802-1, 22-821, Trp-290, CHEBI:29947|Tyr-466/Tyr-586/Tyr-588/Tyr-656/Tyr-657/Tyr-733/Tyr-769/Tyr-779, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2029862 "PR:000061082 located_in GO:0005886"
is_a: PR:P21802-1 ! fibroblast growth factor receptor 2 isoform 1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens