[Term]
id: PR:000061160
name: eukaryotic translation initiation factor 2-alpha kinase 1 phosphorylated 1 (human)
def: "A eukaryotic translation initiation factor 2-alpha kinase 1 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-486 and Thr-488 of the amino acid sequence represented by UniProtKB:Q9BQI3-1 and that includes at least 1 additional phosphorylated threonine. Example: UniProtKB:Q9BQI3-1, Thr-486/Thr-488, MOD:00047|MOD:00047." [PRO:DNx, Reactome:R-HSA-9648894]
comment: Category=organism-modification.
synonym: "hEIF2AK1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-T,T486,T488-EIF2AK1" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9648894]
synonym: "UniProtKB:Q9BQI3, Thr-486/Thr-488, MOD:00047|MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:Q9BQI3-1, Thr-486/Thr-488, MOD:00047|MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9648894 "PR:000061160 located_in GO:0005829"
is_a: PR:Q9BQI3 ! eukaryotic translation initiation factor 2-alpha kinase 1 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens