[Term]
id: PR:000061219
name: sonic hedgehog protein sequence variant F377S, signal peptide removed ubiquitinated form (human)
def: "A sonic hedgehog protein (human) that has a Ser residue at the position equivalent to Phe-377 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Phe-377, CHEBI:29999|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387351, Reactome:R-HSA-5387364]
comment: Category=organism-modification.
synonym: "hSHH/var:F377S/SigPep-/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "ub-SHH(24-462) P377S" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-5387351, Reactome:R-HSA-5387364]
synonym: "UniProtKB:Q15465, 24-462, Phe-377, CHEBI:29999|MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5387351 "PR:000061219 located_in GO:0005788"
xref: Reactome:R-HSA-5387364 "PR:000061219 located_in GO:0005829"
is_a: PR:Q15465 ! sonic hedgehog protein (human)
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens