[Term]
id: PR:000061599
name: RAC-alpha serine/threonine-protein kinase sequence variant E17K phosphorylated 2 (human)
def: "A RAC-alpha serine/threonine-protein kinase (human) that has a Lys residue at the position equivalent to Glu-17 of the amino acid sequence represented by UniProtKB:P31749-1 and that has been phosphorylated on the residues at the positions equivalent to Thr-308 and Ser-473. Example: UniProtKB:P31749-1, Glu-17, CHEBI:29967|Thr-308, MOD:00047|Ser-473, MOD:00046." [PRO:DNx, Reactome:R-HSA-2243935, Reactome:R-HSA-2399994]
comment: Category=organism-modification.
synonym: "hAKT1/var:E17K/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "p-T308,S473-AKT1 E17K" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-2243935, Reactome:R-HSA-2399994]
synonym: "UniProtKB:P31749, Glu-17, CHEBI:29967|Thr-308, MOD:00047|Ser-473, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P31749-1, Glu-17, CHEBI:29967|Thr-308, MOD:00047|Ser-473, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2243935 "PR:000061599 located_in GO:0005829"
xref: Reactome:R-HSA-2399994 "PR:000061599 located_in GO:0005654"
is_a: PR:P31749 ! RAC-alpha serine/threonine-protein kinase (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens