[Term]
id: PR:000061605
name: coagulation factor IX, signal peptide removed carboxylated and hydroxylated 1 (human)
def: "A coagulation factor IX (human) that has had the signal peptide removed and that has been carboxylated on the residues at the positions equivalent to Glu-53, Glu-54, Glu-61, Glu-63, Glu-66, Glu-67, Glu-72, Glu-73, Glu-76, Glu-79, Glu-82 and Glu-86, and hydroxylated on the residue at the position equivalent to Asp-110 of the amino acid sequence represented by UniProtKB:P00740-1. Example: UniProtKB:P00740-1, 29-461, Glu-53/Glu-54/Glu-61/Glu-63/Glu-66/Glu-67/Glu-72/Glu-73/Glu-76/Glu-79/Glu-82/Glu-86, MOD:00041|Asp-110, MOD:00036." [PRO:DNx, Reactome:R-HSA-159726, Reactome:R-HSA-159866]
comment: Category=organism-modification.
synonym: "hF9/SigPep-/CbxHy:1" EXACT PRO-short-label [PRO:DNx]
synonym: "12xCbxE-3D-F9(29-461)" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-159726, Reactome:R-HSA-159866]
synonym: "UniProtKB:P00740, 29-461, Glu-53/Glu-54/Glu-61/Glu-63/Glu-66/Glu-67/Glu-72/Glu-73/Glu-76/Glu-79/Glu-82/Glu-86, MOD:00041|Asp-110, MOD:00036" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00740-1, 29-461, Glu-53/Glu-54/Glu-61/Glu-63/Glu-66/Glu-67/Glu-72/Glu-73/Glu-76/Glu-79/Glu-82/Glu-86, MOD:00041|Asp-110, MOD:00036" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-159726 "PR:000061605 located_in GO:0005796"
xref: Reactome:R-HSA-159866 "PR:000061605 located_in GO:0005788"
is_a: PR:P00740 ! coagulation factor IX (human)
relationship: has_part MOD:00036 ! (2S,3R)-3-hydroxyaspartic acid
relationship: has_part MOD:00041 ! L-gamma-carboxyglutamic acid
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens