[Term]
id: PR:000061629
name: histone H3.3, initiator methionine removed asymmetrically-dimethylated and dimethylated 1 (human)
def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been asymmetrically-dimethylated on the residue at the position equivalent to Arg-3 and dimethylated on the residue at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-3, MOD:00077|Lys-5, MOD:00084." [PRO:DNx, Reactome:R-HSA-8936573]
comment: Category=organism-modification.
synonym: "hH3.3/InitMet-/Me2Me2a:1" EXACT PRO-short-label [PRO:DNx]
synonym: "Me2K5,Me2aR2-H3F3A" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-8936573]
synonym: "UniProtKB:P84243, 2-136, Arg-3, MOD:00077|Lys-5, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8936573 "PR:000061629 located_in GO:0005654"
is_a: PR:P84243 ! histone H3.3 (human)
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine
relationship: has_part MOD:00077 ! asymmetric dimethyl-L-arginine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens