[Term]
id: PR:000061826
name: platelet-derived growth factor receptor alpha sequence variant Y288C, signal peptide removed phosphorylated 1 (human)
def: "A platelet-derived growth factor receptor alpha (human) that has a Cys residue at the position equivalent to Tyr-288 of the amino acid sequence represented by UniProtKB:P16234-1, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Tyr-572, Tyr-574, Tyr-720, Tyr-731, Tyr-742, Tyr-754, Tyr-762, Tyr-768, Tyr-849, Tyr-988, and Tyr-1018. Example: UniProtKB:P16234-1, 24-1089, Tyr-288, CHEBI:29950|Tyr-572/Tyr-574/Tyr-720/Tyr-731/Tyr-742/Tyr-754/Tyr-762/Tyr-768/Tyr-849/Tyr-988/Tyr-1018, MOD:00048." [PRO:DNx, Reactome:R-HSA-9672027]
comment: Category=organism-modification.
synonym: "hPDGFRA/var:Y288C/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-11Y PDGFRA Y288C" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9672027]
synonym: "UniProtKB:P16234, 24-1089, Tyr-288, CHEBI:29950|Tyr-572/Tyr-574/Tyr-720/Tyr-731/Tyr-742/Tyr-754/Tyr-762/Tyr-768/Tyr-849/Tyr-988/Tyr-1018, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P16234-1, 24-1089, Tyr-288, CHEBI:29950|Tyr-572/Tyr-574/Tyr-720/Tyr-731/Tyr-742/Tyr-754/Tyr-762/Tyr-768/Tyr-849/Tyr-988/Tyr-1018, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9672027 "PR:000061826 located_in GO:0005789"
is_a: PR:P16234 ! platelet-derived growth factor receptor alpha (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens