[Term]
id: PR:000061944
name: mothers against decapentaplegic homolog 2 sequence variant A354T, initiator methionine removed phosphorylated 1 (human)
def: "A mothers against decapentaplegic homolog 2 (human) that has a Thr residue at the position equivalent to Ala-354 of the amino acid sequence represented by UniProtKB:Q15796-1, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-465 and Ser-467. Example: UniProtKB:Q15796-1, 2-467, Ala-354, CHEBI:30013|Ser-465/Ser-467, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315474]
comment: Category=organism-modification.
synonym: "hSMAD2/var:A354T/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-S465,S467-SMAD2 A354T" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-3315474]
synonym: "UniProtKB:Q15796, 2-467, Ala-354, CHEBI:30013|Ser-465/Ser-467, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:Q15796-1, 2-467, Ala-354, CHEBI:30013|Ser-465/Ser-467, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3315474 "PR:000061944 located_in GO:0005829"
is_a: PR:Q15796 ! mothers against decapentaplegic homolog 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens