[Term]
id: PR:000062480
name: histone H3.3, initiator methionine removed phosphorylated and trimethylated 1 (human)
def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Thr-12 and trimethylated on the residue at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-10, MOD:00083|Thr-12, MOD:00047." [PRO:DNx, Reactome:R-HSA-5625758]
comment: Category=organism-modification.
synonym: "hH3.3/InitMet-/Me3Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-T12,Me3K-10-H3F3A" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-5625758]
synonym: "UniProtKB:P84243, 2-136, Lys-10, MOD:00083|Thr-12, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5625758 "PR:000062480 located_in GO:0005654"
is_a: PR:P84243 ! histone H3.3 (human)
relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens