[Term]
id: PR:000062485
name: prothrombin, signal peptide removed carboxylated 1 (human)
def: "A prothrombin (human) that has had the signal peptide removed and that has been carboxylated on the residues at the positions equivalent to Glu-49, Glu-50, Glu-57, Glu-59, Glu-62, Glu-63, Glu-68, Glu-69, Glu-72, and Glu-75 of the amino acid sequence represented by UniProtKB:P00734. UniProtKB:P00734, 25-622, Glu-49/Glu-50/Glu-57/Glu-59/Glu-62/Glu-63/Glu-68/Glu-69/Glu-72/Glu-75, MOD:00041." [PRO:DNx, Reactome:R-HSA-159800, Reactome:R-HSA-159841]
comment: Category=organism-modification.
synonym: "hF2/SigPep-/Cbx:1" EXACT PRO-short-label [PRO:DNx]
synonym: "10xCbxE-F2(25-622)" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-159800, Reactome:R-HSA-159841]
synonym: "UniProtKB:P00734, 25-622, Glu-49/Glu-50/Glu-57/Glu-59/Glu-62/Glu-63/Glu-68/Glu-69/Glu-72/Glu-75, MOD:00041" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-159800 "PR:000062485 located_in GO:0005788"
xref: Reactome:R-HSA-159841 "PR:000062485 located_in GO:0005796"
is_a: PR:P00734 ! prothrombin (human)
relationship: has_part MOD:00041 ! L-gamma-carboxyglutamic acid
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens