[Term]
id: PR:000062648
name: apolipoprotein E sequence variant S112R, signal peptide removed form (human)
def: "An apolipoprotein E (human) that has an Arg residue at the position equivalent to Ser-112 of the amino acid sequence represented by UniProtKB:P02649 and that has had the signal peptide removed. UniProtKB:P02649, 19-317, Ser-112, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-9711070]
comment: Category=organism-modification.
synonym: "hAPOE/var:S112R/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "APOE-4" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9711070]
synonym: "UniProtKB:P02649, 19-317, Ser-112, CHEBI:29952" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9711070 "PR:000062648 located_in GO:0005576"
is_a: PR:P02649 ! apolipoprotein E (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens