[Term]
id: PR:000062805
name: coagulation factor VIII sequence variant S603R, signal peptide removed form (human)
def: "A coagulation factor VIII (human) that has an Arg residue at the position equivalent to Ser-603 of the amino acid sequence represented by UniProtKB:P00451-1 and that has had the signal peptide removed. Example: UniProtKB:P00451-1, 20-2351, Ser-603, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-9661964]
comment: Category=organism-modification.
synonym: "hF8/var:S603R/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "F8 S603R" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9661964]
synonym: "UniProtKB:P00451, 20-2351, Ser-603, CHEBI:29952" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00451-1, 20-2351, Ser-603, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9661964 "PR:000062805 located_in GO:0005788"
is_a: PR:P00451 ! coagulation factor VIII (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens